Preformulation Studies for Pharmaceutical Industry
- 5.0
- (4+ reviews)
- Created by Aydan Ozden
- Language: English
Description
Preformulation studies are very important for the development of a pharmaceutical dosage forms in the pharmaceutical industry. This course will help you to understand preformulation development approach with basic concepts of preformulation studies of the Pharma Industry.
Each drug substance has intrinsic chemical and physical characteristics that must be considered before the development of a pharmaceutical formulation. Drug product is formulated using the information gained during the preformulation studies and with the consideration of the dose or doses, dosage form, and route of administration desired for the clinical studies and for the proposed marketed product. Pharmaceutics includes the scientific and technological aspects of the design, compounding, and manufacture of dosage forms.
In the scope of this course, most important physicochemical properties of the drug substance such as solubility, permeability, ionization constant, crystality, polymorphism, amorphous, particle size, particle shape, particle surface area and bulk tapped density & flow evaluation have been discussed.
These aspects in the design of dosage forms are discussed in the scope of this course.
COURSE CONTENT
Physicochemical Properties of the Drug Substance
Topic 1: Solubility
Topic 2: Permeability
Topic 3: Ionization Constant
Topic 4: Crystality
Topic 5: Polymorphism
Topic 6: Amorphous
Topic 7: Particle Size
Topic 8: Particle Shape
Topic 9: Particle Surface Area
Topic 10: Bulked Tapped Density & Flow Evaluation
Course Info
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